Santa Fe de Antioquia Vacations from $587

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Your Santa Fe de Antioquia Vacation

Lock in a Santa Fe de Antioquia vacation package and get set to experience all this city has to offer. Think about staying in the neighborhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. Bridge of the West, Cathedral of Santa Fe de Antioquia and Iglesia de Santa Bárbara are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia vacation plans into action!

The Latest Santa Fe de Antioquia vacation packages

Price found within the past 48 hours. Click for updated prices.
Farum Hotels

Farum Hotels

3.5 out of 5
Laureles
Price was $1,187, price is now $587 per person
$587
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
7.8/10 Good! (31 reviews)
The staff was absolutely amazing ! Valentina was my favourite ! She made an extra effort to make my stay much more pleasant!

Reviewed on Oct 9, 2025

Encanto House in Provenza by Nowa

Encanto House in Provenza by Nowa

2 out of 5
El Poblado
Price was $3,909, price is now $1,888 per person
$1,888
per person
Oct 1 - Oct 7
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
No reviews

Revellion by EP

Revellion by EP

4 out of 5
El Poblado
Price was $1,629, price is now $799 per person
$799
per person
Sep 20 - Sep 26
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
10/10 Exceptional! (2 reviews)
Great place. Great location. We loved it

Reviewed on Jul 7, 2026

Devú

Devú

5 out of 5
El Poblado
Save 100% on your flight
Price was $2,032, price is now $1,135 per person
$1,135
per person
Sep 1 - Sep 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Medellín (MDE)
10/10 Exceptional! (14 reviews)
We really enjoyed our stay at Devu Hotel — it’s a fantastic hotel apartment. The facility is clean, the location is excellent, and the service is superb, meeting all of our expectations. The location couldn’t be more convenient, close to everywhere we needed to go. The apartment itself was clean, well-maintained, and comfortable throughout our stay. What really stood out was the service. The customer service was phenomenal across the board — from the front desk to housekeeping. Most importantly, the manager, Mateo, went above and beyond, providing excellent service and making our stay extremely comfortable. We will definitely be back soon and highly recommend Devu Hotel to anyone looking for a great stay!

Reviewed on Jul 13, 2026

6br penthouse 1 block lleras park

6br penthouse 1 block lleras park

2.5 out of 5
El Poblado
Save 100% on your flight
Price was $1,120, price is now $642 per person
$642
per person
Sep 20 - Sep 26
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
No reviews

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Stay near popular Santa Fe de Antioquia attractions

Bridge of the West

9.0/10 (19 reviews)
After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area.
See properties

What to do in Santa Fe de Antioquia

Tour Santa Fe de Antioquia

Tour Santa Fe de Antioquia

$150
per adult
Tour Santa Fe de Antioquia
Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour

Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour

$148
per adult
Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour
Private Coffee & Panel Tour Near Medellin All Inclusive

Private Coffee & Panel Tour Near Medellin All Inclusive

$150
per adult
Private Coffee & Panel Tour Near Medellin All Inclusive
See all activities in Santa Fe de Antioquia

Santa Fe de Antioquia Hotel Deals

Ivanna Hotel Campestre - Santa Fe de Antioquia

Ivanna Hotel Campestre - Santa Fe de Antioquia

4.5 out of 5
Via Anza Vereda, KM 1, Obregon Santa Fe de Antioquia Antioquia
Fully refundable
$75 nightly
The price is $75 total per night from Aug 11 to Aug 12
$75 total
Aug 11 - Aug 12
Ivanna Hotel Campestre - Santa Fe de Antioquia
Arde La Selva

Arde La Selva

4 out of 5
km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $193 total per night from Aug 3 to Aug 4
$193 total
Aug 3 - Aug 4
9.8/10 Exceptional! (32 reviews)
"the experience was amazing, I'll go back without question, it's a beautiful place to stay for a night or just for a Sunday"

Reviewed on Jul 2, 2026

Arde La Selva
Hotel Mariscal Robledo

Hotel Mariscal Robledo

3 out of 5
Cra 12 No 9 70 Santa Fe de Antioquia Antioquia
$111 nightly
The price is $111 total per night from Jul 15 to Jul 16
$111 total
Jul 15 - Jul 16
9.4/10 Exceptional! (226 reviews)
"Todo espectacular . Los baños de las habitaciones necesitan un poco de renovación ."

Reviewed on Jul 2, 2026

Hotel Mariscal Robledo
See all 511 properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Fe de Antioquia Vacation Packages

Santa Fe de Antioquia Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Enrique Olaya Herrera Airport (EOH)
Population
11,800
Max Temp Winter
70ºF
Max Temp Summer
75ºF
Top Sights
Cathedral of Santa Fe de Antioquia, Museo Juan del Corral and San Jeronimo Park

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Frequently asked questions

How much does a Santa Fe de Antioquia vacation package cost?
Offering excellent value package deals from $587 on Expedia, you'll be thrilled with how little a vacation to Santa Fe de Antioquia costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Fe de Antioquia?
You can generally find lower rates and better availability in June, July and October. Explore our cheap Santa Fe de Antioquia vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Fe de Antioquia?
Generally, a handful of days is great for a Santa Fe de Antioquia vacation. With a well-planned itinerary, you can check out all the leading attractions such as Bridge of the West, as well as explore some hidden gems along the way.
Is it worth booking a vacation package to Santa Fe de Antioquia?
Boasting a host of highlights starting with its excellent history, Santa Fe de Antioquia is a good vacation destination. Whether you'd like to check out sights such as Bridge of the West and Cathedral of Santa Fe de Antioquia or take the path less traveled, you'll have loads to see and do on your Santa Fe de Antioquia vacation.
How to find the best Santa Fe de Antioquia package deals?
Use Expedia's filters to help you find some unbeatable Santa Fe de Antioquia package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your adventure for midweek, or browse for Santa Fe de Antioquia package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Fe de Antioquia vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll typically land a better deal than booking each component individually. And you'll still have the flexibility to create a customized Santa Fe de Antioquia vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Santa Fe de Antioquia?
Land incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Santa Fe de Antioquia escape.
How to plan a trip to Santa Fe de Antioquia?

  1. Choose your dates: The things you'd like to do in Santa Fe de Antioquia and your favorite season will help you decide when to travel.
  2. Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your accommodations will probably be the largest expense during your trip to Santa Fe de Antioquia.
  3. Discover Santa Fe de Antioquia using our trip planning tool: Gain insights into the leading attractions and best properties for your trip to Santa Fe de Antioquia. You can also save your favorite places, collaborate with family and friends and manage your plans in one place.
  4. Set the duration of your trip: Start by listing all the activities and sights you want to experience in Santa Fe de Antioquia. Then, estimate how long you'll need at each, as well as any travel time.
  5. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to find a Santa Fe de Antioquia vacation package that brings all your bookings together.
  6. Book experiences or activities ahead of time: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on Santa Fe de Antioquia's highlights. Find all the incredible things to do in Santa Fe de Antioquia in Santa Fe de Antioquia with our dedicated travel guide.

Does Expedia offer Book Now, Pay Later Santa Fe de Antioquia vacation packages?
Your Santa Fe de Antioquia trip should be an escape from your daily routine, not a reason for money worries. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.