Santa Fe de Antioquia Vacations from $657
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Your Santa Fe de Antioquia Vacation
Lock in a Santa Fe de Antioquia vacation package and get set to experience all this city has to offer. Think about staying in the neighborhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. Bridge of the West, Cathedral of Santa Fe de Antioquia and Iglesia de Santa Bárbara are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia vacation plans into action!
The Latest Santa Fe de Antioquia vacation packages
Price found within the past 48 hours. Click for updated prices.
2bedroom with pooltable 1 block -Lleras
El Poblado
$745,261
per person
Nov 23 - Nov 29
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
10/10 Exceptional! (1 review)
The apartment was perfect for the price. There is only one AC unit in the apartment but does have fans in the bedrooms. Staff was nice and attentive. Location is great and easy to get to Provenza, close to multiple Pharmacy's.
Reviewed on Mar 26, 2026
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See all available trips from Columbus to Santa Fe de Antioquia
View all tripsStay near popular Santa Fe de Antioquia attractions
Bridge of the West
9.0/10 (19 reviews)
After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area.
Cathedral of Santa Fe de Antioquia
9.0/10 (28 reviews)
You can learn about the history of Santa Fe de Antioquia with a trip to Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area.
Church of Our Lady of Chinquinquira
9.2/10 (19 reviews)
Church of Our Lady of Chinquinquira is just one of the places to see in Santa Fe de Antioquia, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or visit its monuments.
Bolivar Square
9.2/10 (30 reviews)
Learn about the local history of Santa Fe de Antioquia with a stop at Bolivar Square. Stroll along the riverfront or experience the area's festivals.
Iglesia de Santa Bárbara
9.4/10 (17 reviews)
After visiting Iglesia de Santa Bárbara, make a plan to see the other sights and activities in Santa Fe de Antioquia. Wander the riverfront and parks while you're in the area.
Casa Atanasio Girardot
8.6/10 (9 reviews)
You can spend an afternoon browsing the exhibits at Casa Atanasio Girardot during your trip to Santa Fe de Antioquia.
Museo Juan del Corral
9.4/10 (10 reviews)
You can study the exhibits at Museo Juan del Corral, a museum with a story of its own, during your travels to Santa Fe de Antioquia. Stroll along the riverfront or experience the area's festivals.
Catedral Basílica Metropolitana de la Inmaculada Concepción
9.2/10 (19 reviews)
Catedral Basílica Metropolitana de la Inmaculada Concepción is just one of the places to see in Santa Fe de Antioquia, so why not enjoy the other things to explore during your travels?
What to do in Santa Fe de Antioquia
Private Coffee & Panel Tour Near Medellin All Inclusive
$150
per adult
Santa Fe de Antioquia Hotel Deals
Arde La Selva
km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia
Fully refundableReserve now, pay when you stay
$174 nightly
$174 total
Oct 9 - Oct 10
Ivanna Hotel Campestre - Santa Fe de Antioquia
Via Anza Vereda, KM 1, Obregon Santa Fe de Antioquia Antioquia
Fully refundable
$71 nightly
$71 total
Sep 15 - Sep 16
7.6/10 Good! (9 reviews)
"Amazing staff, Swimming pool and spa Hot tub Wonderful area secluded Relaxing atmosphere with all the amenities"
Reviewed on Aug 30, 2026
Hotel Boutique Al Alma
#9-50 Cra. 8 Santa Fe de Antioquia Antioquia
$202 nightly
$202 total
Sep 20 - Sep 21
9.4/10 Exceptional! (64 reviews)
"Great place! Staff was awsone. We had a wonderful time."
Reviewed on Aug 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Fe de Antioquia Vacation Packages
Santa Fe de Antioquia Essential Information
Language | Spanish |
|---|---|
Currency | Colombian pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Enrique Olaya Herrera Airport (EOH) |
Population | 11,800 |
Max Temp Winter | 70ºF |
Max Temp Summer | 75ºF |
Top Sights | Cathedral of Santa Fe de Antioquia, Museo Juan del Corral and San Jeronimo Park |
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Frequently asked questions
How much does a Santa Fe de Antioquia vacation package cost?
Offering excellent value package deals from $657 on Expedia, you'll be thrilled with how little a vacation to Santa Fe de Antioquia costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Santa Fe de Antioquia?
You can generally find lower rates and better availability in June, July and October. Explore our cheap Santa Fe de Antioquia vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Fe de Antioquia?
Generally, a handful of days is great for a Santa Fe de Antioquia vacation. With a well-planned itinerary, you can check out all the leading attractions such as Bridge of the West, as well as explore some hidden gems along the way.
Is it worth booking a vacation package to Santa Fe de Antioquia?
Boasting a host of highlights starting with its excellent history, Santa Fe de Antioquia is a good vacation destination. Whether you'd like to check out sights such as Bridge of the West and Cathedral of Santa Fe de Antioquia or take the path less traveled, you'll have loads to see and do on your Santa Fe de Antioquia vacation.
How to find the best Santa Fe de Antioquia package deals?
Use Expedia's filters to help you find some unbeatable Santa Fe de Antioquia package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your adventure for midweek, or browse for Santa Fe de Antioquia package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Fe de Antioquia vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your flight, hotel and car rental into one great-value price and you could save hundreds of dollars. You'll typically land a better deal than booking each component individually. And you'll still have the flexibility to create a customized Santa Fe de Antioquia vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Santa Fe de Antioquia?
Land incredible bargains by reserving your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Santa Fe de Antioquia escape.
How to plan a trip to Santa Fe de Antioquia?
- Choose your dates: The things you'd like to do in Santa Fe de Antioquia and your favorite season will help you decide when to travel.
- Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to activities and airfares. Your accommodations will probably be the largest expense during your trip to Santa Fe de Antioquia.
- Discover Santa Fe de Antioquia using our trip planning tool: Gain insights into the leading attractions and best properties for your trip to Santa Fe de Antioquia. You can also save your favorite places, collaborate with family and friends and manage your plans in one place.
- Set the duration of your trip: Start by listing all the activities and sights you want to experience in Santa Fe de Antioquia. Then, estimate how long you'll need at each, as well as any travel time.
- Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to find a Santa Fe de Antioquia vacation package that brings all your bookings together.
- Book experiences or activities ahead of time: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on Santa Fe de Antioquia's highlights. Find all the incredible things to do in Santa Fe de Antioquia in Santa Fe de Antioquia with our dedicated travel guide.
Does Expedia offer Book Now, Pay Later Santa Fe de Antioquia vacation packages?
Your Santa Fe de Antioquia trip should be an escape from your daily routine, not a reason for money worries. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.
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- Medellin Botanical Garden
- Miguel Angel Builes Ethnographic Museum
- San Jeronimo Church
- Visit Belmira
- Santafé Mall
- Atanasio Giradot Stadium
- Visit Sopetrán
- Bello Vacations
- Hospital Pablo Tobon Uribe
- Volador's Hill Eco Park
- Visit Santa Fe de Antioquia
- Pedro Nel Gómez House Museum
- Visit Olaya
- Church of Our Lady of Chinquinquira
- Museo Juan del Corral
- El Volador Hill
- Botero Plaza
- Pueblito Paisa
- Visit San Jerónimo
- San Pedro Vacations
- Mariposario Selva Viva
- Olaya Vacations
- Medellín Vacations
- Arvi Park
- Minor Basilica of Our Lady of the Assumption
- Casa Atanasio Girardot
- Cathedral of Santa Fe de Antioquia
- San Jeronimo Park
- Bridge of the West
- Catedral Basílica Metropolitana de la Inmaculada Concepción
- El Gaitero Ecopark
- Marco Fidel Suárez Hut Museum
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
